What is SubMagna HMW™?
This oil-based vehicle, created by PCCA, was designed expressly to improve the way high molecular-weight (HMW) drugs, such semaglutide, are absorbed into the bloodstream through the mucosal lining of the mouth.
SubMagna HMW™ may be able to transfer peptides—like semaglutide—into and through human gingival and oral tissue, according to recent in vitro tissue models.
Semaglutide, and other similar medications, have seen unprecedented demand globally, leading to widespread shortages. In addition, most of these medications are delivered via syringe, which may create complications for patients.
The only oral formulation available, Rybelsus®, is estimated to reach no more than 1% absorption through the stomach, lowering its efficacy. Sublingual delivery avoids these issues and allows for much greater absorption.
Why deliver semaglutide sublingually?
Our compounded formulation of sublingual semaglutide contains just two major ingredients--Rybelsus® and SubMagna HMW™--and flavoring. As this is a prescription item, please discuss with your doctor if this option might be right for you. You may also call us with any additional questions.
What is semaglutide?
Semaglutide is a medication that offers potential benefits for patients with conditions such as Type 2 Diabetes and Weight Loss. It is the active ingredient of medications such as Ozempic®, Wegovy® and Rybelsus®.​
How does sublingual administration work?
Sublingual administration involves placing the medication under the tongue, which is absorbed directly into the bloodstream, bypassing the digestive system.
What are the advantages of sublingual administration?
Sublingual administration can lead to a faster onset of action, increased bioavailability compared to oral administration, and a reduced risk of gastrointestinal side effects compared to injectable administration.
What are the main ingredients in your compounded sublingual semaglutide?
Our compounded sublingual semaglutide is a mixture of two main ingredients: RYBELSUS® and Submagna HMW, and flavoring.
Is compounded sublingual semaglutide FDA-approved?
The FDA does not review compounded medication, including Subsema, for safety or efficacy. However, licensed pharmacists prepare compounded medications according to strict quality standards.
How can I learn more about compounded sublingual semaglutide?
Please feel free to give us a call for any more information related to compounded sublingual semaglutide.
Can patients anywhere in your service area access compounded sublingual semaglutide?
Yes, patients in our service area, which currently encompasses the states of PA and NJ, can receive compounded sublingual semaglutide through Health on South Rx (HSRX). We are committed to providing quality compounded medications to patients in need.
Yes, patients in our service area, which currently encompasses the states of PA and NJ, can receive compounded sublingual semaglutide through Health on South Rx (HSRX). We are committed to providing quality compounded medications to patients in need.
What should patients do if they would like more information about compounded sublingual semaglutide?
Patients interested in more information about compounded sublingual semaglutide can contact HSRX directly by email at info@healthonsouthrx.com or by calling/texting at 215-496-9595 for more information and assistance.
Are there any potential risks or side effects associated with compounded sublingual semaglutide?
As with any medication, compounded sublingual semaglutide may have potential risks and side effects. Common side effects experienced with GLP-1 agonists include nausea, vomiting, and constipation. Patients should consult with their healthcare provider before starting any new medication.
Does insurance cover compounded sublingual semaglutide?
Insurance coverage for compounded medications may vary. Please contact the pharmacy today for details on our out-of-pocket cost for a 30-day supply.
RYBELSUS®, is a registered trademark of Novo Nordisk A/S. No compounded medication is reviewed by FDA for
safety or efficacy. SubMagnaTM HMW is a trademark of Kingdom Licensing.